AdButler.ads.push({handler: function(opt){ AdButler.register(165395, 174783, [300,250], 'placement174783'+opt.place, opt); }, opt: { place: plc174783++, keywords: abkw, domain: 'ads.ecigmedia.com', click:'CLICK_MACRO_PLACEHOLDER' }}); © 2017 Ejuice Econnoisseur. 106-111. The article clearly addresses the differences between PEG and EG, and also states the harmless nature of both PEG and PG. Both ethylene glycol and propylene glycol are alcoholic compounds which have two –OH groups per molecule. This danger is present in PEG, but as stated above, not enough to cause harm. Synonyms : Synonyms for propylene glycol include. It is the most common moisture-carrying vehicle other than water itself and helps prevent moisture loss in products as well as binding to moisture and holding it to the skin. Pentylene Glycol uses and safety in cosmetics assesed by Truth In Aging Free shipping on all domestic orders over $49 ... "It has properties that are similar to a known allergen--propylene glycol--although it is considered by some to be less irritating or allergenic." It is not, in fact, used in any anti-freeze. im getting mine from virgin vape. It is a hydrophilic ingredient, which means that it binds well to water. Please keep your facts straight. Turns out the Propylene Glycol did no measurable damage to my colon or lower intestinal tract. Propylene Glycol vs. Propanediol. Came here searching for info on PEG and of course google leads me to a page made by an asshole moron. FDA UNII. This research seems to suggest that pentylene glycol may have this property, which may explain its ability to work as a preservative. Their molecular formulas are different; thus they have some different physical properties. Acetyl glucosamine is a skin-replenishing ingredient that helps to reduc... What Is Acetyl Hexapeptide 8? The concern arises when propylene glycol is heated up and inhaled. I keep reading warnings, many by the uneducated masses of parrots populating the green face of the Earth and some by the supposedly educated, medical professionals of the world, which impress upon those being warned that the liquid used in E-cigarettes is also used in antifreeze, making it extremely toxic to human beings… and animals, too, allegedly. Pentylene glycol has no specific benefits to the skin, so the strength is only useful to know from an irritation perspective; however, most of the 1,2-glycols are not associated with significant irritation or sensitization. 31, iss. Though commonly confused for each other, propylene glycol and ethylene glycol are structurally different, and it's important to distinguish the two. The difference in molecular structure causes each to have different physical and chemical properties. OTHER COMPANIES’ MARKS USED ON THIS SITE REMAIN THE INTELLECTUAL PROPERTY OF THEIR RESPECTIVE OWNERS. UNII-50C1307PZG. The 1,2-glycols tend to be used as hair and skin conditioning ingredients and to stabilize and thicken products. What I was pointing out was that despite PEG NOT BEING DANGEROUS, the E-cig industry switched to PG just to placate the worry-warts out there. PG is metabolised by the human body into chemicals that are naturally occurring in normal, human metabolic functions. Synergetic ingredients: Works well with most ingredients. The Final Word on Propylene Glycol vs. Polyethylene Glycol, Product Safety Assessment- Propylene Glycol, Deposition and Fate of Inhaled Ethylene Glycol Vapor and Condensation Aerosol in the Rat. PE and kidneys. Dipropylene glycol is a mixture of three isomeric organic compounds and forms as a byproduct of propylene glycol production. 12 Skincare Ingredients You May Want to Avoid. Pentylene glycol also has the added benefit of acting as a preservative, which minimizes the need to add other preservatives to formulations. The. Pentylene glycol. It is a colorless, odorless, slightly syrupy liquid that is a bit thicker than water. What is propylene glycol? ‘Margin of safety of pentylene glycol using measurements of cutaneous absorption and volatility’, Regulatory Toxicology and Pharmacology, vol. Propanediol and Propylene Glycol have the same Empirical Formula (C3H8O2), the molecular structure of each compound is different. They found that one of the main ingredients in E-liquid was polyethylene glycol, which is used in antifreeze and is fairly toxic to humans in large quantities. Not only that, but I fact check the sources’ sources as well. Compare/Contrast. Pillai, R, Schmaus, G, Pfeiffer, A, Lange, S & Trunet, A, 2013. What Are Parabens – And Are They Bad For You? To help you choose the correct glycol product please refer to the chart below. Side by Side Comparison – Dipropylene Glycol vs Propylene Glycol in Tabular Form 5. EC 226-285-3. Johnson, W et al. However, there are industries that like more a particular glycol than the other one. Propylene glycol is one of those chemicals. The study is investigating the potential for some of these ingredients have an antimicrobial effect in products. At ChemWorld, we provide different grades of Propylene Glycol. Vegetable Glycerin (VG) e-juice. ‘Safety Assessment of 1, 2-Glycols as Used in Cosmetics’, International Journal of Toxicology, vol. Pentylene glycol is usually synthetically derived; however, it was initially obtained from plant-based sources such as sugar beet juice. Both products are two chemical compounds used as some low temperature heat transfer fluids. Propylene glycol is added to food products, cosmetics, and even de-icing agents, like antifreeze. Polyethylene glycol is, in fact, used in antifreeze because it lowers the freezing temperature of water. Cosmetic Ingredient Review, 2011. Hence the picture above. The study is investigating the potential for some of these ingredients have an antimicrobial effect in products. Both of them possess low vapor pressure, also they contain high boiling points and the ability to lower the freeze point of water. The E-cigarette industry answered by changing that ingredient to propylene glycol, a much safer alternative. Pentylene Glycol – the even more compatible “Green variant” Recently, there is an even more compatible version of pentylene glycol, based on by-products from manufacturing processes based on sugarcane residues and corn spindles. 147s-168s. Cosmetic Ingredient Review, 2011. Of course, they also did so in an effort to shut the ANTZ (Anti-Nicotine and Tobacco Zealots) up… a move which ultimately failed because they have abandoned all attention to scientific evidence in exchange for a vendetta against the industry as a whole. Ethylene glycol has two carbon atoms, and propylene glycol has three carbon atoms per molecule. The FDA, otherwise known as the opponents to the E-cigarette industry) as GRAS (Generally Recognized as Safe). Propylene glycol is used by the chemical, food, and pharmaceutical industries as an antifreeze when leakage might lead to contact with food. Propylene glycol is an FDA-approved additive for military dietary rations (Agency for Toxic Substances and Disease Registry 1997). There are 16 other 1,2-glycols, only four are used in skincare. Antifreeze which uses PEG to lower the freezing point of water is generally dyed a blue/green color (we’ve all seen it on our driveway at one point or another) to indicate toxicity and danger. It is a diol, or double alcohol, which means that people who are not permitted to use alcohol would not be able to use any fragrance oils with it as a carrier oil. Why is there a difference in the amount of propylene glycol that is acceptable in the U.S. vs. Europe? To help you understand better and learn some background information, pros and cons, and differences we created this tutorial. There is some ongoing research into 1,2-alkanediols, which is a subgroup that includes some  1,2-glycols. & Kunze, G, 2017. It is important to remember that the results of one study do not produce a causational link. The results were not particularly promising for the industry (as these chemicals did show up, especially at high-voltages), but one caveat did stick out. EXCLUDING INTELLECTUAL PROPERTY OWNED BY OTHERS, ALL SITE CONTENT IS COPYRIGHTED OR LICENSED FOR USE BY THE OWNER OF THIS SITE. Antimicrobial and Preservative This irritation is rare and usually occurs in skin types that are already sensitized or prone to irritation. Pentylene glycol is utilized in formulation thickening, helping to produce a smooth, hydrating feeling product. This is however, not always the case. Because propylene glycol is bio-degradable and is also environmentally friendly to lakes and rivers. For example, in aeroplane de-icing propylene glycol is used for both removing ice and contaminates from an aeroplane as well as being used during winter and periods of snowfall to actively prevent accumulation of snow and ice. Please go fuck yourself with this article. 1,5-Pentanediol is the organic compound with the formula HOCH 2 CH 2 CH 2 CH 2 CH 2 OH. 0005343920 . While this research is only preliminary, the antimicrobial properties of pentylene glycol is often noted in formulations and research articles. Ethylene Glycol has been known to be lethal in doses as low as 786 mg/kg. document.write('<'+'div id="placement174783'+plc174783+'">'); The carbon chain can vary in length; for example, propylene glycol, which has a chain length of three, hexylene glycol, which has a chain length of six and pentylene glycol, which has a chain length of five. Dr. O’Keefe: “Food additives are regulated in the U.S. based on their function and in what food category they can be used. 106-111. Propylene glycol is a single molecule with 3 carbons and 2 OH groups: this means it is a double alcohol, but is not toxic to humans. Although they share some physical properties, they have very distinctive features and it is very important to identify these compounds accurately due to the toxicity of propylene glycol. Pentylene glycol does not have any evidence to suggest toxicity or carcinogenicity. Polyethylene glycol is used in a wide variety of medical applications and is completely safe. 3-01-00-02191 (Beilstein Handbook Reference) AI3-03317. if (!window.AdButler){(function(){var s = document.createElement("script"); s.async = true; s.type = "text/javascript";s.src = 'http://ads.ecigmedia.com/app.js';var n = document.getElementsByTagName("script")[0]; n.parentNode.insertBefore(s, n);}());} TO LEARN MORE ABOUT THE DETAILS OF THESE RELATIONSHIPS AND HOW PRODUCTS ARE RANKED ON OUR SITE, PLEASE READ THE "FULL DISCLOSURE" AND "METHODOLOGY" SECTIONS. There are four different propylene glycol. It occurs … No, this effect has only been seen in PG. Registry Numbers. Systematic Names. –Two-week aerosol inhalation study on polyethylene glycol (PEG) 3350 in F-344 rats. Propylene glycol is also used to make polyester compounds and as a base for de-icing solutions. If you have sensitive skin that is prone to irritation, consult your dermatologist about whether this ingredient is best for you. 2, pp. Propylene glycol (IUPAC name: propane-1,2-diol), according to the US National Library of Medicine and the Agency for Toxic Substances and Disease Registry, is a synthetic liquid substance that absorbs water. It is a colorless liquid with a mild odor. ‘Margin of safety of pentylene glycol using measurements of cutaneous absorption and volatility’, Regulatory Toxicology and Pharmacology, vol. ALL RIGHTS RESERVED. The CIR Expert Panel has evaluated the safety of the 1,2-glycol, propylene glycol and polypropylene glycols and concluded that these ingredients are safe for use in cosmetic products at concentrations up to 50.0%. Other Registry Number. It is a hydrophilic ingredient, which means that it binds well to water. 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